Brimonidine Tartrate
目录号: A15033
α-adrenergic receptor 激动剂
酒石酸布莫尼丁是一种高度选择性的α-肾上腺素受体激动剂,对α2A肾上腺受体的EC50为0.45 nM,用于治疗开角型青光眼或眼内高压。
| Discription | Brimonidine Tartrate is a highly selective α-adrenergic receptor agonist with EC50 of 0.45 nM for the α2A adrenoreceptor, and used to treat open-angle glaucoma or ocular hypertension. |
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| 目录号 | A15033 |
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| 分子式 | C15H16BrN5O6 |
| 分子量 | 442.22 |
| CAS号 | 70359-46-5 |
| SMILES | C1CN=C(N1)NC2=C(C3=NC=CN=C3C=C2)Br.C(C(C(=O)O)O)(C(=O)O)O |
| 其他名称 | AGN190342 tartrate, UK14304 tartrate |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 84 mg/mL (189.95 mM) | |
| Water | 72 mg/mL (162.81 mM) | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.61 mL | 113.07 mL | 226.13 mL |
| 0.5 mM | 4.52 mL | 22.61 mL | 45.23 mL |
| 1 mM | 2.26 mL | 11.31 mL | 22.61 mL |
| 5 mM | 0.45 mL | 2.26 mL | 4.52 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2