Brincidofovir (CMX001)
目录号: A13326
Brincidofovir 是 cidofovir 的前体药物。通过与脂质结合,该化合物旨在细胞内释放 cidofovir,从而实现更高的细胞内浓度和更低的血浆浓度,有效提高其对 dsDNA 病毒 的活性,同时增加口服生物利用度。
Discription | Brincidofovir is a prodrug of cidofovir. Conjugated to a lipid, the compound is designed to release cidofovir intracellularly, allowing for higher intracellular and lower plasma concentrations of cidofovir, effectively increasing its activity against dsDNA viruses, as well as oral bioavailability. | |||||
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Cell Research |
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目录号 | A13326 |
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分子式 | C27H52N3O7P |
分子量 | 561.7008 |
CAS号 | 444805-28-1 |
SMILES | CCCCCCCCCCCCCCCCOCCCOP(=O)(CO[C@@H](CN1C=CC(=NC1=O)N)CO)O |
其他名称 | CMX001, Cidofovir-HDP, hexadecyloxypropyl-cidofovir |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2