Brivanib alaninate (BMS-582664)

目录号: A10162

VEGFR inhibitor

Brivanib alaninate (BMS-582664) Chemical Structure

CAS NO. 649735-63-7

Brivanib alaninate (BMS-582664) is a dual tyrosine kinase inhibitor of VEGFR and FGFR signaling.

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,680.00
25 mg
¥ 3,680.00
50 mg
¥ 6,880.00
10mM * 1mL in DMSO
¥ 1,380.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Brivanib alaninate (BMS-582664) is a dual tyrosine kinase inhibitor of VEGFR and FGFR signaling.
Targets
VEGFR2 Flk1 FGFR1 VEGFR1
25 nM89 nM148 nM380 nM
In vitro (25°C) DMSO 88 mg/mL (199.33 mM)
Water <1 mg/mL (<1 mM)
Ethanol 88 mg/mL (199.33 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.65 mL 113.25 mL 226.5 mL
0.5 mM 4.53 mL 22.65 mL 45.3 mL
1 mM 2.27 mL 11.33 mL 22.65 mL
5 mM 0.45 mL 2.27 mL 4.53 mL

*The above data is based on the productmolecular weight 441.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10162
MECHANISM OF ACTION Inhibitor
M. Wt 441.5
Formula C22H24FN5O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 649735-63-7
Synonyms BMS582664
SMILES CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OC[C@@H](C)OC(=O)[C@H](C)N)C

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