Brivanib alaninate (BMS-582664)
目录号: A10162
VEGFR 抑制剂
Brivanib alaninate (BMS-582664) 是一种针对 VEGFR 和 FGFR 信号传导的双重酪氨酸激酶抑制剂。
| Discription | Brivanib alaninate (BMS-582664) is a dual tyrosine kinase inhibitor of VEGFR and FGFR signaling. | ||
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| 目录号 | A10162 |
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| 分子式 | C22H24FN5O4 |
| 分子量 | 441.5 |
| CAS号 | 649735-63-7 |
| SMILES | CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OC[C@@H](C)OC(=O)[C@H](C)N)C |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 83 mg/mL (188 mM) | |
| Water | Insoluble | ||
| Ethanol | 83 mg/mL (188 mM) | ||
| In vivo | 0.5% methylcellulose+0.2% Tween 80 | 9 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.65 mL | 113.25 mL | 226.5 mL |
| 0.5 mM | 4.53 mL | 22.65 mL | 45.3 mL |
| 1 mM | 2.27 mL | 11.33 mL | 22.65 mL |
| 5 mM | 0.45 mL | 2.27 mL | 4.53 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2