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Brivanib alaninate (BMS-582664)


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产品目录号: A10162


产品名 目录号 价格 数量
Brivanib alaninate 5mg A10162-5
¥ 900.00
Brivanib alaninate 10mg A10162-10
¥ 1,680.00
Brivanib alaninate 25mg A10162-25
¥ 3,680.00
Brivanib alaninate 50mg A10162-50
¥ 6,880.00
Brivanib alaninate 10mM * 1mL in DMSO A10162-10mM-D
¥ 1,380.00



Brivanib alaninate (BMS-582664) is a dual tyrosine kinase inhibitor of VEGFR and FGFR signaling.

Brivanib alaninate (BMS-582664)




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Chemical Information

目录号 A10162
Mechanism of action Inhibitor
分子量 441.5
化学分子式 C22H24FN5O4
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 649735-63-7
Synonyms BMS582664
SMILES code CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OC[C@@H](C)OC(=O)[C@H](C)N)C
化学名称 (S)-(R)-1-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl)oxy)propan-2-yl 2-aminopropanoate


Brivanib alaninate (BMS-582664) is a dual tyrosine kinase inhibitor of VEGFR and FGFR signaling.
25 nM89 nM148 nM380 nM


Solubility (25°C) * In vitro DMSO 88 mg/mL (199.33 mM)
Water <1 mg/mL (<1 mM)
Ethanol 88 mg/mL (199.33 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.65 mL 113.25 mL 226.5mL
0.5 mM 4.53 mL 22.65 mL 45.3 mL
1 mM 2.27 mL 11.33 mL 22.65 mL
5 mM 0.45 mL 2.27 mL 4.53 mL

*The above data is based on the productmolecular weight 441.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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