Brivanib (BMS-540215)

目录号: A10254

VEGFR-2 inhibitor

Brivanib (BMS-540215) Chemical Structure

CAS NO. 649735-46-6

Brivanib (BMS-540215) is a VEGFR -2 inhibitor with an IC50 of 25 nM and Ki of 26 nM.

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,600.00
50 mg
¥ 4,500.00
200 mg
¥ 12,000.00
10mM * 1mL in DMSO
¥ 1,260.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Brivanib (BMS-540215) is a VEGFR -2 inhibitor with an IC50 of 25 nM and Ki of 26 nM.
Targets
Target Value
VEGFR2IC50: 25nM
Flk1IC50: 89nM
FGFR1IC50: 148nM
VEGFR1IC50: 380nM
EGFRIC50: >1.9μM
LCKIC50: >2.5μM
PDGFRβIC50: >6μM
PKCαIC50: >25μM
JAK3IC50: >50μM
In vitro DMSO 74 mg/mL (199.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (8.09 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27 mL 134.99 mL 269.98 mL
0.5 mM 5.4 mL 27 mL 54 mL
1 mM 2.7 mL 13.5 mL 27 mL
5 mM 0.54 mL 2.7 mL 5.4 mL

*The above data is based on the productmolecular weight 370.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10254
MECHANISM OF ACTION Inhibitor
M. Wt 370.4
Formula C19H19FN4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 649735-46-6
Synonyms BMS540215
SMILES CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NN4C3=C(C(=C4)OC[C@@H](C)O)C

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