BRL-15572

目录号: A11178

5-HT1D receptor 拮抗剂

BRL-15572 Chemical Structure

CAS NO. 193611-72-2

BRL-15572是一种选择性的h5-HT1D拮抗剂,相对于h5-HT1B表现出60倍的选择性,对一系列其他受体类型的亲和力很小或没有亲和力。

库存: 缺货

规格 价格
5 mg
¥ 500.00
10 mg
¥ 700.00
50 mg
¥ 2,600.00
100 mg
¥ 4,200.00
10mM * 1mL in DMSO
¥ 1,030.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

BRL-15572是一种选择性的h5-HT1D拮抗剂,相对于h5-HT1B表现出60倍的选择性,对一系列其他受体类型的亲和力很小或没有亲和力。
Targets
Target Value
5-HT1Dpki: 7.9
5-HT1Apki: 7.7
5-HT2Bpki: 7.4
5-HT2Apki: 6.6
5-HT7pki: 6.3
5-HT2Cpki: 6.2
5-HT1Bpki: 6.1
5-HT1Fpki: 6
5-HT6pki: 5.9
5-HT1Epki: 5.2
In vitro (25°C) DMSO 96 mg/mL (200.05 mM)
Water <1 mg/mL (<1 mM)
Ethanol 40 mg/mL (83.35 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 20 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.55 mL 112.76 mL 225.52 mL
0.5 mM 4.51 mL 22.55 mL 45.1 mL
1 mM 2.26 mL 11.28 mL 22.55 mL
5 mM 0.45 mL 2.26 mL 4.51 mL

*The above data is based on the productmolecular weight 443.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11178
MECHANISM OF ACTION Antagonist
M. Wt 443.42
Formula C25H27ClN2O.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 193611-72-2
Synonyms BRL15572
SMILES C1CN(CCN1CC(C(C2=CC=CC=C2)C3=CC=CC=C3)O)C4=CC(=CC=C4)Cl.Cl.Cl

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