BRL-15572 dihydrochloride

Name: BRL-15572 dihydrochloride
SKU: A11178

目录号: A11178

5-HT1D receptor 拮抗剂

BRL-15572 dihydrochloride Chemical Structure

CAS NO. 193611-72-2

BRL-15572是一种选择性的h5-HT1D拮抗剂，相对于h5-HT1B表现出60倍的选择性，对一系列其他受体类型的亲和力很小或没有亲和力。

库存：缺货

规格	价格
5 mg	￥ 500.00
10 mg	￥ 700.00
50 mg	￥ 2,600.00
100 mg	￥ 4,200.00
10mM * 1mL in DMSO	￥ 1,030.00

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产品详情

生物活性

BRL-15572是一种选择性的h5-HT1D拮抗剂，相对于h5-HT1B表现出60倍的选择性，对一系列其他受体类型的亲和力很小或没有亲和力。

Targets

Target	Value
5-HT1D	pki: 7.9
5-HT1A	pki: 7.7
5-HT2B	pki: 7.4
5-HT2A	pki: 6.6
5-HT7	pki: 6.3
5-HT2C	pki: 6.2
5-HT1B	pki: 6.1
5-HT1F	pki: 6
5-HT6	pki: 5.9
5-HT1E	pki: 5.2

溶解度 *

In vitro (25°C)	DMSO	89 mg/mL (185.46 mM)
	Water	Insoluble
	Ethanol	37 mg/mL (77.1 mM)
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	19 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.84 mL	104.19 mL	208.39 mL
0.5 mM	4.17 mL	20.84 mL	41.68 mL
1 mM	2.08 mL	10.42 mL	20.84 mL
5 mM	0.42 mL	2.08 mL	4.17 mL

*The above data is based on the productmolecular weight 479.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11178
作用机制	Antagonist (拮抗剂)
M. Wt	479.87
Formula	C25H29Cl3N2O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	193611-72-2
Synonyms	BRL15572
SMILES	C1CN(CCN1CC(C(C2=CC=CC=C2)C3=CC=CC=C3)O)C4=CC(=CC=C4)Cl.Cl.Cl