BS-181 hydrochloride

Name: BS-181 hydrochloride
SKU: A21988
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A21988

CDK7 抑制剂

BS-181 氢氯化物是一种高度选择性的 CDK7 抑制剂，其 IC50 为 21 nM，对 CDK7 的选择性比 CDK1、CDK2、CDK4、CDK5、CDK6 或 CDK9 高出 40 倍以上。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥245.00	现货
5mg	¥455.00	现货
10mg	¥840.00	现货
25mg	¥1,960.00	现货
50mg	¥3,290.00	现货
100mg	¥4,760.00	现货
*10mM 1mL in DMSO**	¥490.00	现货
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Data Sheet

SDS

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生物活性

Discription

BS-181 hydrochloride is a highly selective CDK7 inhibitor with IC50 of 21 nM, and > 40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9.

Targets

Target	Value

产品信息

目录号	A21988
分子式	C22H33ClN6
分子量	416.99
CAS号	1397219-81-6
SMILES	CC(C1=C(N=C(C=C2NCC3=CC=CC=C3)NCCCCCCN)N2N=C1)C.[H]Cl
其他名称	BS181, BS 181
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	81 mg/mL (194.24 mM)
	Water	3 mg/mL (7.19 mM)
	Ethanol	Warmed: 22 mg/mL (52.75 mM)
In vivo	1% DMSO+30% polyethylene glycol+1% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.98 mL	119.91 mL	239.81 mL
0.5 mM	4.8 mL	23.98 mL	47.96 mL
1 mM	2.4 mL	11.99 mL	23.98 mL
5 mM	0.48 mL	2.4 mL	4.8 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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