BTSA1

目录号: A16835

Bcl-2 modulator

BTSA1

BTSA1 Chemical Structure

CAS NO. 314761-14-3

BTSA1是经过药理优化的BAX激活剂,可与N末端激活位点高亲和力和特异性结合,并诱导BAX发生构象变化,从而导致BAX介导的细胞凋亡。它有效促进白血病细胞系和患者样品中的细胞凋亡,同时保留健康细胞。

库存: 现货

规格 价格 数量
2 mg
¥ 900.00
5 mg
¥ 1,800.00
10 mg
¥ 3,200.00
50 mg
¥ 12,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

BTSA1是经过药理优化的BAX激活剂,可与N末端激活位点高亲和力和特异性结合,并诱导BAX发生构象变化,从而导致BAX介导的细胞凋亡。它有效促进白血病细胞系和患者样品中的细胞凋亡,同时保留健康细胞。
In vitro DMSO 77 mg/mL (178.85 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.23 mL 116.14 mL 232.28 mL
0.5 mM 4.65 mL 23.23 mL 46.46 mL
1 mM 2.32 mL 11.61 mL 23.23 mL
5 mM 0.46 mL 2.32 mL 4.65 mL

*The above data is based on the productmolecular weight 430.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16835
作用机制 Modulator (调节剂)
M. Wt 430.51
Formula C21H14N6OS2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 314761-14-3
SMILES O=C(N(C1=NC(C2=CC=CC=C2)=CS1)N=C/3C4=CC=CC=C4)C3=N\NC5=NC=CS5

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