BTSA1
目录号: A16835
Bcl-2 modulator
BTSA1 是一种药理学优化的 BAX 激活剂，它能高亲和力和特异性地结合到 BAX 的 N-末端激活位点，并诱导 BAX 发生构象变化，从而导致 BAX-介导的凋亡。它能有效促进白血病细胞系和患者样本中的凋亡，同时对健康细胞无害。
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生物活性
| Discription | BTSA1 is a pharmacologically optimized BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis. It effectively promotes apoptosis in leukemia cell lines and patient samples while sparing healthy cells. | |||||
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| Cell Research |
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产品信息
| 目录号 | A16835 |
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| 分子式 | C21H14N6OS2 |
| 分子量 | 430.51 |
| CAS号 | 314761-14-3 |
| SMILES | O=C(N(C1=NC(C2=CC=CC=C2)=CS1)N=C/3C4=CC=CC=C4)C3=N\NC5=NC=CS5 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 77 mg/mL (178.85 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.23 mL | 116.14 mL | 232.28 mL |
| 0.5 mM | 4.65 mL | 23.23 mL | 46.46 mL |
| 1 mM | 2.32 mL | 11.61 mL | 23.23 mL |
| 5 mM | 0.46 mL | 2.32 mL | 4.65 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
Keywords: 购买 BTSA1 | BTSA1 供应商 | BTSA1 花费 | BTSA1 生产商 | 订购 BTSA1 | BTSA1 代理商
| 购买 314761-14-3 | 314761-14-3 供应商 | 314761-14-3 花费 | 314761-14-3 生产商 | 订购 314761-14-3 | 314761-14-3 代理商