Budigalimab (ABBV 181; PR 1648817) is a humanized recombinant IgG1 monoclonal antibody specifically designed to target the programmed cell death 1 (PD-1) receptor. This antibody features a modified Fc region with a mutation that diminishes Fc receptor interactions and effector function inhibition. By effectively blocking the interaction between PD-1 and its ligand PD-L1, Budigalimab exhibits potent anti-tumor activity. It is primarily utilized in research focused on various solid tumors, providing a valuable tool for oncology studies.
Budigalimab (ABBV 181; PR 1648817) is a humanized recombinant IgG1 monoclonal antibody specifically designed to target the programmed cell death 1 (PD-1) receptor. This antibody features a modified Fc region with a mutation that diminishes Fc receptor interactions and effector function inhibition. By effectively blocking the interaction between PD-1 and its ligand PD-L1, Budigalimab exhibits potent anti-tumor activity. It is primarily utilized in research focused on various solid tumors, providing a valuable tool for oncology studies.
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