BX-517
目录号: A12881
PDK1 抑制剂
BX-517 是一种强效且选择性的 PDK1 抑制剂,它与蛋白质的 ATP 结合口袋结合(IC50 = 6 nM)。
Discription | BX-517 is a potent and selective inhibitor of PDK1 that binds to the ATP binding pocket of the protein (IC50 = 6 nM). |
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目录号 | A12881 |
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分子式 | C15H14N4O2 |
分子量 | 282.3 |
CAS号 | 850717-64-5 |
SMILES | CC(=C1C2=C(C=CC(=C2)NC(=O)N)NC1=O)C3=CC=CN3 |
其他名称 | BX517, BX 517 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 54 mg/mL (191.29 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 35.42 mL | 177.12 mL | 354.23 mL |
0.5 mM | 7.08 mL | 35.42 mL | 70.85 mL |
1 mM | 3.54 mL | 17.71 mL | 35.42 mL |
5 mM | 0.71 mL | 3.54 mL | 7.08 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2