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BX471是一种有效的选择性非肽CCR1拮抗剂（对于人CCR1，Ki = 1 nM），对CCR1的选择性是CCR2，CCR5和CXCR4的250倍。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.99 mL | 114.97 mL | 229.94 mL |
| 0.5 mM | 4.6 mL | 22.99 mL | 45.99 mL |
| 1 mM | 2.3 mL | 11.5 mL | 22.99 mL |
| 5 mM | 0.46 mL | 2.3 mL | 4.6 mL |
*The above data is based on the productmolecular weight 434.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14409 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 434.89 |
| Formula | C21H24ClFN4O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 217645-70-0 |
| Synonyms | BX-471, BX 471 |
| SMILES | CC1CN(CCN1C(=O)COC2=C(C=C(C=C2)Cl)NC(=O)N)CC3=CC=C(C=C3)F |
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