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CCR1 拮抗剂

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产品目录号: A14409


产品名 目录号 价格 数量
BX471 5mg A14409-5
¥ 800.00
BX471 10mg A14409-10
¥ 1,500.00
BX471 25mg A14409-25
¥ 3,000.00



BX471 is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1), exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.





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Chemical Information

目录号 A14409
Mechanism of action Antagonist
分子量 434.89
化学分子式 C21H24ClFN4O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 217645-70-0
Synonyms BX-471, BX 471
化学名称 2R)-1-[[2-[(Aminocarbonyl)amino]-4-chlorophenoxy]acetyl]-4-[(4-fluorophenyl)methyl]-2-methylpiperazine


BX471 is a potent, selective non-peptide CCR1 antagonist (Ki = 1 nM for human CCR1), exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.99 mL 114.97 mL 229.94mL
0.5 mM 4.6 mL 22.99 mL 45.99 mL
1 mM 2.3 mL 11.5 mL 22.99 mL
5 mM 0.46 mL 2.3 mL 4.6 mL

*The above data is based on the productmolecular weight 434.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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