BYL719 (Alpelisib)

Name: BYL719 (Alpelisib)
SKU: A11328
Price: 315 CNY
Rating: 5 (7 reviews)

目录号: A11328

PI3K 抑制剂

7 篇发表文献

BLY719 是一种口服生物利用度的磷脂酰肌醇3激酶（PI3K）抑制剂，具有潜在的抗肿瘤活性。

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Grouped product items
规格	价格	库存
5mg	¥315.00	现货
10mg	¥420.00	现货
25mg	¥490.00	现货
50mg	¥630.00	现货
100mg	¥1,050.00	现货
200mg	¥1,890.00	现货
500mg	¥3,255.00	现货
1g	¥4,760.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

Other Forms of BYL719 (Alpelisib)

Alpelisib hydrochloride

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用BYL719 (Alpelisib)发表的7篇文献

Natasa Stojanovic Guzvic, .et al. , Mol Oncol, 2024, Oct 5 PMID: 39367702

Majid Momeny, .et al. , EMBO Mol Med, 2024, Jun 17 PMID: 38886591

Kevin J Pridham, .et al. , iScience, 2024, May 7;27(6):109921 PMID: 38812542

Elaheh S Abutorabi, .et al. , Mol Biol Rep, 2023, May;50(5):4073-4082 PMID: 36877344

Lisann Pelzl, .et al. , J Thromb Haemost, 2022, Feb;20(2):387-398 PMID: 34752677

J Wei, .et al. , bioRxiv, 2018, 2018

Pridham KJ, .et al. , Neuro Oncol, 2018, Mar 27;20(4):494-505 PMID: 29016844

生物活性

Discription

BLY719 is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11328
分子式	C19H22F3N5O2S
分子量	441.5
CAS号	1217486-61-7
SMILES	CC1=C(SC(=N1)NC(=O)N2CCC[C@H]2C(=O)N)C3=CC(=NC=C3)C(C)(C)C(F)(F)F
其他名称	BYL-719
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	77 mg/mL (174.41 mM)
	Water	Insoluble
	Ethanol	2 mg/mL (4.53 mM)
In vivo	5%DMSO+40%PEG300+5%Tween80+50%ddH2O	4.1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.65 mL	113.25 mL	226.5 mL
0.5 mM	4.53 mL	22.65 mL	45.3 mL
1 mM	2.27 mL	11.33 mL	22.65 mL
5 mM	0.45 mL	2.27 mL	4.53 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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