BYL719 (Alpelisib)

目录号: A11328

PI3K Inhibitor

BYL719 (Alpelisib)

BYL719 (Alpelisib) Chemical Structure

CAS NO. 1217486-61-7

BLY719 is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity.

库存: 现货

规格 价格 数量
5 mg
¥ 600.00
10 mg
¥ 900.00
25 mg
¥ 1,200.00
50 mg
¥ 1,400.00
10mM * 1mL in DMSO
¥ 600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

BLY719 is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity.
Targets
PI3Kα (Cell-free assay)
5 nM
In vitro (25°C) DMSO 88 mg/mL (199.33 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (4.53 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.65 mL 113.25 mL 226.5 mL
0.5 mM 4.53 mL 22.65 mL 45.3 mL
1 mM 2.27 mL 11.33 mL 22.65 mL
5 mM 0.45 mL 2.27 mL 4.53 mL

*The above data is based on the productmolecular weight 441.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11328
MECHANISM OF ACTION Inhibitor
M. Wt 441.5
Formula C19H22F3N5O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1217486-61-7
Synonyms BYL-719
SMILES CC1=C(SC(=N1)NC(=O)N2CCC[C@H]2C(=O)N)C3=CC(=NC=C3)C(C)(C)C(F)(F)F

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