CA-4948

目录号: A17005

IRAK4 抑制剂

CA-4948

CA-4948 Chemical Structure

CAS NO. 1801343-74-7

CA-4948是一种有效的,口服活性的白介素1受体相关激酶4(IRAK4)抑制剂。与GBC-DLBCL和ABC/GCB DLBCL PDX模型相比,CA-4948在所测试的五个ABC-DLBCL PDX模型中的四个模型中显示出最大的功效。

库存: 现货

规格 价格 数量
5 mg
¥ 1,800.00
10 mg
¥ 3,200.00
50 mg
¥ 9,800.00
100 mg
¥ 16,800.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

CA-4948是一种有效的,口服活性的白介素1受体相关激酶4(IRAK4)抑制剂。与GBC-DLBCL和ABC/GCB DLBCL PDX模型相比,CA-4948在所测试的五个ABC-DLBCL PDX模型中的四个模型中显示出最大的功效。
In vitro DMSO 27 mg/mL (64.68 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.96 mL 119.78 mL 239.56 mL
0.5 mM 4.79 mL 23.96 mL 47.91 mL
1 mM 2.4 mL 11.98 mL 23.96 mL
5 mM 0.48 mL 2.4 mL 4.79 mL

*The above data is based on the productmolecular weight 417.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A17005
作用机制 Inhibitor (抑制剂)
M. Wt 417.43
Formula C21H19N7O3
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1801343-74-7
Synonyms CA 4948, CA4948
SMILES O=C(C1=CC=CC(C2=CC=C(N)N=C2)=N1)NC3=CN=C4C(OC(N5CCOCC5)=N4)=C3

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