CADD522
CADD522 是一种强效的 runt-related transcription factor-2 (RUNX2)-DNA 结合抑制剂，其 IC50 为 10 nM。CADD522 表现出抗肿瘤活性。
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生物活性
| Discription | CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM. CADD522 exhibits antitumor activity. |
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产品信息
| 目录号 | A19399 |
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| 分子式 | C15H13Cl2NO3 |
| 分子量 | 326.17 |
| CAS号 | 199735-88-1 |
| SMILES | ClC1=C(Cl)C=CC(NC(C2C(C3)C=CC3C2C(O)=O)=O)=C1 |
| 其他名称 | CADD 522, CADD-522 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 58 mg/mL (177.82 mM) | |
| Water | Insoluble | ||
| Ethanol | 58 mg/mL (177.82 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.66 mL | 153.29 mL | 306.59 mL |
| 0.5 mM | 6.13 mL | 30.66 mL | 61.32 mL |
| 1 mM | 3.07 mL | 15.33 mL | 30.66 mL |
| 5 mM | 0.61 mL | 3.07 mL | 6.13 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 199735-88-1 | 199735-88-1 供应商 | 199735-88-1 花费 | 199735-88-1 生产商 | 订购 199735-88-1 | 199735-88-1 代理商