Calcifediol
目录号: A11367
Calcifediol 是维生素 D3 的主要循环代谢物,作为具有明显 Ki 值为 3.9 μM 的竞争性抑制剂。它还抑制 PTH 分泌和 mRNA(ED50=2 nM)。
Discription | Calcifediol is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 μM. It also suppresses PTH secretion and mRNA (ED50=2 nM) | ||
---|---|---|---|
Targets |
|
目录号 | A11367 |
---|---|
分子式 | C27H44O2 |
分子量 | 400.64 |
CAS号 | 19356-17-3 |
SMILES | C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](CCC3=C)O)C |
其他名称 | 25-Hydroxyvitamin D3, Calcidiol |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 74 mg/mL (184.7 mM) | |
Water | Insoluble | ||
Ethanol | 18 mg/mL (44.93 mM) | ||
In vivo | 2% DMSO+30% PEG 300+5% Tween+ddH2O | 4 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.96 mL | 124.8 mL | 249.6 mL |
0.5 mM | 4.99 mL | 24.96 mL | 49.92 mL |
1 mM | 2.5 mL | 12.48 mL | 24.96 mL |
5 mM | 0.5 mL | 2.5 mL | 4.99 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2