Canagliflozin hemihydrate

Name: Canagliflozin hemihydrate
SKU: A16817
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A16817

SGLT2 抑制剂

半水合卡格列净是卡格列净的半水合形式，它是一种 SGLT2抑制剂，在无细胞试验中对hSGLT2的IC50为2.2 nM，对hSGLT1的选择性高达413倍。

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Grouped product items
规格	价格	库存
100mg	¥175.00	现货
500mg	¥525.00	现货
1g	¥805.00	现货
*10mM 1mL in DMSO**	¥210.00	现货
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Data Sheet

SDS

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生物活性

Discription	Canagliflozin hemihydrate is the hemihydrate form of canagliflozin, which is a SGLT2 inhibitor with IC50 of 2.2 nM for hSGLT2 in a cell-free assay, exhibits 413-fold selectivity over hSGLT1.

产品信息

目录号	A16817
分子式	C48H52F2O11S2
分子量	907.05
CAS号	928672-86-0
SMILES	O[C@H]1C(O[C@@H]([C@H]([C@@H]1O)O)CO)C2=CC=C(C(CC3=CC=C(S3)C4=CC=C(C=C4)F)=C2)C.[H]O[H].O[C@H]5C(O[C@@H]([C@H]([C@@H]5O)O)CO)C6=CC=C(C(CC7=CC=C(S7)C8=CC=C(C=C8)F)=C6)C
其他名称	JNJ 28431754; JNJ-28431754; JNJ28431754; TA 7284; TA-7284; TA7284; JNJ-24831754-ZAE; JNJ-28431754-AAA
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	94 mg/mL (103.63 mM)
	Water	Insoluble
	Ethanol	94 mg/mL (103.63 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	11.02 mL	55.12 mL	110.25 mL
0.5 mM	2.2 mL	11.02 mL	22.05 mL
1 mM	1.1 mL	5.51 mL	11.02 mL
5 mM	0.22 mL	1.1 mL	2.2 mL

Useful Calculator

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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