Capecitabine (Xeloda)

目录号: A10177

Capecitabine (Xeloda) Chemical Structure

CAS NO. 154361-50-9

Capecitabine is a prodrug, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. The activation of capecitabine follows a pathway with three enzymatic steps and two intermediary metabolites, 5'-deoxy-5-fluorocytidine (5'-DFCR) and 5'-deoxy-5-fluorouridine (5'-DFUR), to form 5-fluorouracil.

库存: 现货

规格 价格 数量
1000 mg
¥ 400.00
5000 mg
¥ 1,600.00
10mM * 1mL in DMSO
¥ 590.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Capecitabine is a prodrug, that is enzymatically converted to 5-fluorouracil in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue. The activation of capecitabine follows a pathway with three enzymatic steps and two intermediary metabolites, 5'-deoxy-5-fluorocytidine (5'-DFCR) and 5'-deoxy-5-fluorouridine (5'-DFUR), to form 5-fluorouracil.

靶点信息
Thymidine phosphorylase
In vitro DMSO 72 mg/mL (200.36 mM)
Water 6 mg/mL (16.69 mM)
Ethanol 72 mg/mL (200.36 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.82 mL 139.12 mL 278.24 mL
0.5 mM 5.56 mL 27.82 mL 55.65 mL
1 mM 2.78 mL 13.91 mL 27.82 mL
5 mM 0.56 mL 2.78 mL 5.56 mL

*The above data is based on the productmolecular weight 359.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10177
MECHANISM OF ACTION N/A
M. Wt 359.4
Formula C15H22FN3O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 154361-50-9
Synonyms Captabin
SMILES CCCCCOC(=O)NC1=NC(=O)N(C=C1F)[C@H]2[C@@H]([C@@H]([C@H](O2)C)O)O

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