Caplacizumab (ALX-0681) is a humanized nanobody targeting the von Willebrand factor (vWF), designed to disrupt the interaction between vWF and platelet glycoprotein Ib??. By inhibiting this binding, Caplacizumab effectively prevents vWF-mediated platelet adhesion, thereby reducing the formation of microthrombi. This agent is particularly useful for research focused on thrombotic thrombocytopenic purpura (TTP), offering a valuable tool for investigating the mechanisms and potential treatments of this condition.
Caplacizumab (ALX-0681) is a humanized nanobody targeting the von Willebrand factor (vWF), designed to disrupt the interaction between vWF and platelet glycoprotein Ib??. By inhibiting this binding, Caplacizumab effectively prevents vWF-mediated platelet adhesion, thereby reducing the formation of microthrombi. This agent is particularly useful for research focused on thrombotic thrombocytopenic purpura (TTP), offering a valuable tool for investigating the mechanisms and potential treatments of this condition.
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