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Cariprazine hydrochloride是一种新型的抗精神病药物，对多巴胺D3（Ki = 0.09 nM）和D2（Ki = 0.5 nM）受体具有高选择性和亲和力，对5-羟色胺5-HT（1A）受体具有中等亲和力。
| In vitro | DMSO | 4 mg/mL (8.62 mM) | |
| Water | 3 mg/mL (6.46 mM) | ||
| Ethanol | 3 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.56 mL | 107.79 mL | 215.58 mL |
| 0.5 mM | 4.31 mL | 21.56 mL | 43.12 mL |
| 1 mM | 2.16 mL | 10.78 mL | 21.56 mL |
| 5 mM | 0.43 mL | 2.16 mL | 4.31 mL |
*The above data is based on the productmolecular weight 463.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15036 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 463.87 |
| Formula | C21H33Cl3N4O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1083076-69-0 |
| Synonyms | RGH-188 hydrochloride, RGH 188 hydrochloride, RGH188 hydrochloride |
| SMILES | CN(C)C(=O)NC1CCC(CC1)CCN2CCN(CC2)C3=C(C(=CC=C3)Cl)Cl.Cl |
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