Carotuximab (TRC105) is an IgG1 monoclonal antibody designed to inhibit endoglin (CD105), a critical component of the Smad signaling pathway. This antibody exhibits both immunomodulatory and antineoplastic properties, making it a valuable tool in cancer research and therapy development. Carotuximab targets endoglin-expressing cells, thereby interfering with cellular processes essential for tumor growth and angiogenesis.
Carotuximab (TRC105) is an IgG1 monoclonal antibody designed to inhibit endoglin (CD105), a critical component of the Smad signaling pathway. This antibody exhibits both immunomodulatory and antineoplastic properties, making it a valuable tool in cancer research and therapy development. Carotuximab targets endoglin-expressing cells, thereby interfering with cellular processes essential for tumor growth and angiogenesis.
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