Catumaxomab is a trifunctional IgG2 antibody engineered from mouse and rat heavy and light chains. This antibody exhibits specific binding to human epithelial cell adhesion molecule (EpCAM) and the T-cell receptor CD3. Additionally, the Fc region of Catumaxomab demonstrates affinity for Fc gamma receptors Fc??R1 (CD64), Fc??RIIA (CD32a), and Fc??RIII (CD16). Due to its unique binding properties, Catumaxomab is particularly valuable in the study of epithelial cancers, serving as a potent tool in anti-tumor research applications.
Catumaxomab is a trifunctional IgG2 antibody engineered from mouse and rat heavy and light chains. This antibody exhibits specific binding to human epithelial cell adhesion molecule (EpCAM) and the T-cell receptor CD3. Additionally, the Fc region of Catumaxomab demonstrates affinity for Fc gamma receptors Fc??R1 (CD64), Fc??RIIA (CD32a), and Fc??RIII (CD16). Due to its unique binding properties, Catumaxomab is particularly valuable in the study of epithelial cancers, serving as a potent tool in anti-tumor research applications.
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