CAY10505
目录号: A11196
PI3K 抑制剂
CAY10505 是一种强效的 PI3K 抑制剂，它选择性地抑制 γ 亚型（IC50 = 30 nM），相比之下对 α、β 和 δ 亚型的抑制效果较弱（IC50 分别为 0.94、20 和 20 μM）。
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生物活性
| Discription | CAY10505 is a potent inhibitor of PI3K, selectively inhibiting the γ isoform (IC50 = 30 nM) better than the α, β, and δ isoforms (IC50 = 0.94, 20, and 20 μM, respectively). |
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产品信息
| 目录号 | A11196 |
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| 分子式 | C14H8FNO3S |
| 分子量 | 289.28 |
| CAS号 | 1218777-13-9 |
| SMILES | C1=CC(=CC=C1C2=CC=C(O2)/C=C/3\C(=O)NC(=O)S3)F |
| 其他名称 | CAY-10505 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 53 mg/mL (183.21 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 34.57 mL | 172.84 mL | 345.69 mL |
| 0.5 mM | 6.91 mL | 34.57 mL | 69.14 mL |
| 1 mM | 3.46 mL | 17.28 mL | 34.57 mL |
| 5 mM | 0.69 mL | 3.46 mL | 6.91 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1218777-13-9 | 1218777-13-9 供应商 | 1218777-13-9 花费 | 1218777-13-9 生产商 | 订购 1218777-13-9 | 1218777-13-9 代理商