CAY10603
CAY10603 是一种强效且选择性的 HDAC6 抑制剂，其 IC50 为 2 pM，对其他 HDACs 的选择性超过 200 倍。
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生物活性
| Discription | CAY10603 is a potent and selective HDAC6 inhibitor with IC50 of 2 pM, >200-fold selectivity over other HDACs. | |||||
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| Cell Research |
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产品信息
| 目录号 | A16431 |
|---|---|
| 分子式 | C22H30N4O6 |
| 分子量 | 446.5 |
| CAS号 | 1045792-66-2 |
| SMILES | CC(C)(C)OC(=O)NC1=CC=C(C=C1)C2=CC(=NO2)C(=O)NCCCCCCC(=O)NO |
| 其他名称 | CAY-10603, CAY 10603 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 88 mg/mL (197.08 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 5 mg/mL | ||
| In vivo | 5% DMSO+50% PEG 300+ddH2O | 8 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.4 mL | 111.98 mL | 223.96 mL |
| 0.5 mM | 4.48 mL | 22.4 mL | 44.79 mL |
| 1 mM | 2.24 mL | 11.2 mL | 22.4 mL |
| 5 mM | 0.45 mL | 2.24 mL | 4.48 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1045792-66-2 | 1045792-66-2 供应商 | 1045792-66-2 花费 | 1045792-66-2 生产商 | 订购 1045792-66-2 | 1045792-66-2 代理商