CBR 5884
目录号: A16176
PHGDH 抑制剂
CBR 5884 是一种3-磷酸甘油酸脱氢酶（PHGDH）抑制剂，能够抑制从3-磷酸甘油酸到丝氨酸的合成，其在细胞中的IC50值为33 uM。
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生物活性
| Discription | CBR 5884 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 33 uM. |
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产品信息
| 目录号 | A16176 |
|---|---|
| 分子式 | C14H12N2O4S2 |
| 分子量 | 336.38 |
| CAS号 | 681159-27-3 |
| SMILES | CCOC(=O)C1=C(C(=C(S1)NC(=O)C2=CC=CO2)SC#N)C |
| 其他名称 | CBR-5884, CBR5884 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 58 mg/mL (172.42 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.73 mL | 148.64 mL | 297.28 mL |
| 0.5 mM | 5.95 mL | 29.73 mL | 59.46 mL |
| 1 mM | 2.97 mL | 14.86 mL | 29.73 mL |
| 5 mM | 0.59 mL | 2.97 mL | 5.95 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 681159-27-3 | 681159-27-3 供应商 | 681159-27-3 花费 | 681159-27-3 生产商 | 订购 681159-27-3 | 681159-27-3 代理商