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CBR 5884

PHGDH 抑制剂

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产品目录号: A16176

库存状态:中国现货中国现货

产品名 目录号 价格 数量
CBR 5884 5mg A16176-5
¥ 500.00
CBR 5884 10mg A16176-10
¥ 900.00
CBR 5884 50mg A16176-50
¥ 3,600.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

CBR 5884 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 33 uM.

CBR 5884

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Chemical Information

目录号 A16176
Mechanism of action Inhibitor
分子量 336.38
化学分子式 C14H12N2O4S2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 681159-27-3
Synonyms CBR-5884, CBR5884
SMILES code CCOC(=O)C1=C(C(=C(S1)NC(=O)C2=CC=CO2)SC#N)C
化学名称 ethyl 5-(furan-2-carbonylamino)-3-methyl-4-thiocyanatothiophene-2-carboxylate

生物活性

Description
CBR 5884 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 33 uM.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.73 mL 148.64 mL 297.28mL
0.5 mM 5.95 mL 29.73 mL 59.46 mL
1 mM 2.97 mL 14.86 mL 29.73 mL
5 mM 0.59 mL 2.97 mL 5.95 mL

*The above data is based on the productmolecular weight 336.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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