CC-223

目录号: A13078

mTOR Inhibitor

CC-223 Chemical Structure

CAS NO. 1228013-30-6

CC-223 is a potent mTOR kinase inhibitor (IC50=16 nM), with >150-fold sensitivity over the related lipid kinase PI3K-alpha (IC50=4uM).

库存: 现货

规格 价格 数量
5 mg
¥ 1,200.00
10 mg
¥ 1,900.00
25 mg
¥ 3,900.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

CC-223 is a potent mTOR kinase inhibitor (IC50=16 nM), with >150-fold sensitivity over the related lipid kinase PI3K-alpha (IC50=4uM).
Targets
mTOR cFMS FLT4 DNA-PK PI3K-α
16 nM28 nM651 nM840 nM4.0 μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.16 mL 125.8 mL 251.59 mL
0.5 mM 5.03 mL 25.16 mL 50.32 mL
1 mM 2.52 mL 12.58 mL 25.16 mL
5 mM 0.5 mL 2.52 mL 5.03 mL

*The above data is based on the productmolecular weight 397.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13078
MECHANISM OF ACTION Inhibitor
M. Wt 397.47
Formula C21H27N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1228013-30-6
Synonyms CC 223, CC223
SMILES CC(C)(C1=NC=C(C=C1)C2=CN=C3C(=N2)N(C(=O)CN3)C4CCC(CC4)OC)O

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