产品详情
CC0651 is an allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme. CC0651 potently (IC50=1.72 μM) inhibits the ubiquitination of p27Kip1, as confirmed by dose-response analysis.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.61 mL | 113.05 mL | 226.1 mL |
0.5 mM | 4.52 mL | 22.61 mL | 45.22 mL |
1 mM | 2.26 mL | 11.3 mL | 22.61 mL |
5 mM | 0.45 mL | 2.26 mL | 4.52 mL |
*The above data is based on the productmolecular weight 442.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A21188 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 442.29 |
Formula | C20H21Cl2NO6 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1319207-44-7 |
Synonyms | CC 0651, CC-0651 |
SMILES | ClC1=CC(Cl)=CC(C2=CC=C(C=C2)C[C@@H]([C@@H]([C@H](C(O)=O)O)O)NC(COC)=O)=C1 |
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