CCG215022
目录号: A16189
GRK2/5 抑制剂
CCG215022 是一种强效的 GRK2 和 GRK5 抑制剂。CCG215022 对 GRK2 和 GRK5 表现出纳摩尔级的 IC50 值,并且对其他近缘激酶如 GRK1 和 PKA 有良好的选择性。
Discription | CCG215022 is a potent GRK2 and GRK5 inhibitor. CCG215022 exhibited nanomolar IC50 values against both GRK2 and GRK5 and good selectivity against other closely related kinases such as GRK1 and PKA. | |||||
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Cell Research |
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目录号 | A16189 |
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分子式 | C26H22FN7O3 |
分子量 | 499.51 |
CAS号 | 1813527-81-9 |
SMILES | O=C(C1=C(F)C=CC(C2C(C(NC3=CC=C(NN=C4)C4=C3)=O)=C(C)NC(N2)=O)=C1)NCC5=NC=CC=C5 |
其他名称 | CCG 215022, CCG-215022 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 89 mg/mL (178.18 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 20.02 mL | 100.1 mL | 200.2 mL |
0.5 mM | 4 mL | 20.02 mL | 40.04 mL |
1 mM | 2 mL | 10.01 mL | 20.02 mL |
5 mM | 0.4 mL | 2 mL | 4 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2