CCT128930
目录号: A11031
AKT 抑制剂
CCT128930 是一种 ATP 竞争性 AKT 抑制剂，它是一种高效的先进铅化吡咯并嘧啶化合物，通过针对单个氨基酸差异，实现了对 AKT 相对于 PKA 的选择性。
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生物活性
| Discription | CCT128930 is an ATP-competitive AKT inhibitor that is a potent, advanced lead pyrrolopyrimidine compound exhibiting selectivity for AKT over PKA, achieved by targeting a single amino acid difference. | |||||
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产品信息
| 目录号 | A11031 |
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| 分子式 | C18H20ClN5 |
| 分子量 | 341.8 |
| CAS号 | 885499-61-6 |
| SMILES | C1CN(CCC1(CC2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4 |
| 其他名称 | CCT-128930 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 59 mg/mL (172.59 mM) | |
| Water | Insoluble | ||
| Ethanol | 5 mg/mL (14.63 mM) | ||
| In vivo | 2% DMSO+30% PEG 300+2% Tween 80+ddH2O | 3 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.26 mL | 146.28 mL | 292.57 mL |
| 0.5 mM | 5.85 mL | 29.26 mL | 58.51 mL |
| 1 mM | 2.93 mL | 14.63 mL | 29.26 mL |
| 5 mM | 0.59 mL | 2.93 mL | 5.85 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 885499-61-6 | 885499-61-6 供应商 | 885499-61-6 花费 | 885499-61-6 生产商 | 订购 885499-61-6 | 885499-61-6 代理商