CCT137690

目录号: A11081

Aurora Kinase inhibitor

CCT137690 Chemical Structure

CAS NO. 1095382-05-0

CCT137690 is a highly selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 15 nM, 25 nM and 19 nM. It has little effect on hERG ion-channel.

库存: 现货

规格 价格 数量
5 mg
¥ 850.00
10 mg
¥ 1,100.00
50 mg
¥ 4,000.00
100 mg
¥ 6,250.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

CCT137690 is a highly selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 15 nM, 25 nM and 19 nM. It has little effect on hERG ion-channel.
Targets
Aurora A Aurora C Aurora B
15 nM19 nM25 nM
In vitro (25°C) DMSO 4 mg/mL (7.25 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.13 mL 90.66 mL 181.32 mL
0.5 mM 3.63 mL 18.13 mL 36.26 mL
1 mM 1.81 mL 9.07 mL 18.13 mL
5 mM 0.36 mL 1.81 mL 3.63 mL

*The above data is based on the productmolecular weight 551.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11081
MECHANISM OF ACTION Inhibitor
M. Wt 551.5
Formula C26H31BrN8O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1095382-05-0
Synonyms CCT-137690
SMILES CC1=CC(=NO1)CN2CCN(CC2)C3=C4C(=NC=C3Br)N=C(N4)C5=CC=C(C=C5)N6CCN(CC6)C

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