|Mechanism of action||Inhibitor|
|储存方式||at -20°C 2 years|
|CCT137690 is a highly selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 15 nM, 25 nM and 19 nM. It has little effect on hERG ion-channel.|
|Solubility (25°C) *||In vitro||DMSO||4 mg/mL (7.25 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||<1 mg/mL (<1 mM)|
|In vivo||1% DMSO/30% polyethylene glycol/1% Tween 80||30 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||18.13 mL||90.66 mL||181.32mL|
|0.5 mM||3.63 mL||18.13 mL||36.26 mL|
|1 mM||1.81 mL||9.07 mL||18.13 mL|
|5 mM||0.36 mL||1.81 mL||3.63 mL|
*The above data is based on the productmolecular weight 551.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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