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CCT239065

DNA, RNA Synthesis 抑制剂

158 Customer Reviews
产品目录号: A11147

库存状态:中国现货中国现货

产品名 目录号 价格 数量
CCT239065 5mg A11147-5
¥ 2,000.00
CCT239065 10mg A11147-10
¥ 3,200.00
CCT239065 50mg A11147-50
¥ 8,500.00
CCT239065 100mg A11147-100
¥ 14,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

CCT239065 is a mutant protein kinase inhibitor that inhibits signaling downstream of V600EBRAF in cancer cells, blocking DNA synthesis, and inhibiting proliferation.

CCT239065

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Chemical Information

目录号 A11147
Mechanism of action Inhibitor
分子量 555.7
化学分子式 C29H29N7O3S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1163719-51-4
Synonyms CCT-239065
SMILES code CC1=CC=C(C=C1)N2C(=CC(=N2)C(C)(C)C)NC(=O)NC3=C(C=C(C=C3)OC4=C5C(=NC=C4)NC(=O)C=N5)SC
化学名称 N-[4-[(3,4-dihydro-3-oxopyrido[2,3-b]pyrazin-8-yl)oxy]-2-(methylthio)phenyl]-N-[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-urea

生物活性

Description
CCT239065 is a mutant protein kinase inhibitor that inhibits signaling downstream of V600EBRAF in cancer cells, blocking DNA synthesis, and inhibiting proliferation.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18 mL 89.98 mL 179.95mL
0.5 mM 3.6 mL 18 mL 35.99 mL
1 mM 1.8 mL 9 mL 18 mL
5 mM 0.36 mL 1.8 mL 3.6 mL

*The above data is based on the productmolecular weight 555.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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