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CD-161 is a potent and orally bioavailable BET inhibitor with an IC50s of 28.2 nM and 7.2 nM for BRD4 BD1 and BRD4 BD2, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.96 mL | 114.82 mL | 229.63 mL |
| 0.5 mM | 4.59 mL | 22.96 mL | 45.93 mL |
| 1 mM | 2.3 mL | 11.48 mL | 22.96 mL |
| 5 mM | 0.46 mL | 2.3 mL | 4.59 mL |
*The above data is based on the productmolecular weight 435.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18921 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 435.48 |
| Formula | C26H21N5O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1627716-22-6 |
| Synonyms | CD-161; CD161; CD 161 |
| SMILES | CC1=C(C2=CC3=C(C=C2OC)C4=C(C5=CC=NC6=CC=CC=C56)N=C(C)N=C4N3)C(C)=NO1 |
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