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CDK8/19-IN-1

CDK8/19-IN-1

Name: CDK8/19-IN-1
SKU: A19986

目录号: A19986

CDK8/19 dual inhibitor

CDK8/19-IN-1 Chemical Structure

CAS NO. 1818427-07-4

CDK8/19-IN-1 is a potent, selective and oral bioavailable CDK8/19 dual inhibitor, with IC50s of 0.46 nM, 0.99 nM and 270 nM for CDK8, CDK19 and CDK9, respectively.

库存：现货

规格	价格	数量
1 mg	￥ 3,200.00
5 mg	￥ 9,600.00
10 mg	￥ 16,000.00

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产品仅用于科学研究，不针对患者销售，望谅解.

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生物活性

CDK8/19-IN-1 is a potent, selective and oral bioavailable CDK8/19 dual inhibitor, with IC50s of 0.46 nM, 0.99 nM and 270 nM for CDK8, CDK19 and CDK9, respectively.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.23 mL	116.14 mL	232.29 mL
0.5 mM	4.65 mL	23.23 mL	46.46 mL
1 mM	2.32 mL	11.61 mL	23.23 mL
5 mM	0.46 mL	2.32 mL	4.65 mL

*The above data is based on the productmolecular weight 430.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A19986
M. Wt	430.5
Formula	C19H18N4O4S2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1818427-07-4
SMILES	O=C(C1=C2CCC3=C(SN=C3)C2=C(OC4=CC=C(C(NCCOC)=O)N=C4)S1)N