Asnuciclib (CDKI-73)

Name: Asnuciclib (CDKI-73)
SKU: A21467
Price: 980 CNY
Rating: 5 (288 reviews)

目录号: A21467

CDK9 抑制剂

CDKI-73 是一种强效的 CDK9 抑制剂，Ki 值为 4 nM；显示出对 CLL 细胞的选择性毒性（LD50=80 nM），相比之下，正常 B 细胞和正常 CD34+ 细胞的 LD50 值超过 20 uM。

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Grouped product items
规格	价格	库存
1mg	¥980.00	现货
2mg	¥1,330.00	现货
5mg	¥2,100.00	现货
10mg	¥3,045.00	现货
25mg	¥5,075.00	现货
50mg	¥6,860.00	现货
100mg	¥9,695.00	现货
*10mM 1mL in DMSO**	¥2,205.00	现货
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Data Sheet

SDS

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生物活性

Discription

CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM; shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A21467
分子式	C15H15FN6O2S2
分子量	394.45
CAS号	1421693-22-2
SMILES	CNC1=NC(C)=C(C2=C(F)C=NC(NC3=CC(S(=O)(N)=O)=CC=C3)=N2)S1
其他名称	CDKI73, CDKI 73, LS-007
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	77 mg/mL (195.2 mM)
	Water	Insoluble
	Ethanol	1 mg/mL (2.53 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.35 mL	126.76 mL	253.52 mL
0.5 mM	5.07 mL	25.35 mL	50.7 mL
1 mM	2.54 mL	12.68 mL	25.35 mL
5 mM	0.51 mL	2.54 mL	5.07 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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