CE-245677

Name: CE-245677
SKU: A19377

目录号: A19377

Tie2 and TrkA/B inhibitor

CE-245677 Chemical Structure

CAS NO. 717899-97-3

CE-245677 is a potent reversible inhibitor of Tie2 and TrkA/B kinases with a cellular IC50s of 4.7 and 1 nM.

库存：现货

规格	价格	数量
1 mg	￥ 3,200.00
5 mg	￥ 9,600.00
10 mg	￥ 16,000.00

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生物活性

CE-245677 is a potent reversible inhibitor of Tie2 and TrkA/B kinases with a cellular IC50s of 4.7 and 1 nM.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.48 mL	97.39 mL	194.79 mL
0.5 mM	3.9 mL	19.48 mL	38.96 mL
1 mM	1.95 mL	9.74 mL	19.48 mL
5 mM	0.39 mL	1.95 mL	3.9 mL

*The above data is based on the productmolecular weight 513.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A19377
作用机制	Inhibitor (抑制剂)
M. Wt	513.38
Formula	C24H22Cl2N6O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	717899-97-3
Synonyms	CE245677, CE 245677
SMILES	O=C(NC1=CC=C(Cl)C=C1Cl)NC2=CC(C(C3=CN(C(C)C)C4=NC=NC(N)=C43)=O)=CC=C2OC