Cediranib maleate

Name: Cediranib maleate
SKU: A21857

目录号: A21857

VEGFR inhibitor

Cediranib maleate Chemical Structure

CAS NO. 857036-77-2

Cediranib maleate (AZD-2171 maleate) is a highly potent, orally available VEGFR inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively.

库存：现货

规格	价格	数量
5 mg	￥ 650.00
10 mg	￥ 1,120.00
50 mg	￥ 3,310.00
100 mg	￥ 6,620.00

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生物活性

Cediranib maleate (AZD-2171 maleate) is a highly potent, orally available VEGFR inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively.

溶解度 *

In vitro	DMSO	92 mg/mL (162.37 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.65 mL	88.25 mL	176.5 mL
0.5 mM	3.53 mL	17.65 mL	35.3 mL
1 mM	1.76 mL	8.82 mL	17.65 mL
5 mM	0.35 mL	1.76 mL	3.53 mL

*The above data is based on the productmolecular weight 566.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A21857
作用机制	Inhibitor (抑制剂)
M. Wt	566.58
Formula	C29H31FN4O7
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	857036-77-2
Synonyms	AZD-2171 maleate, AZD2171, AZD 2171
SMILES	O=C(O)/C=C\C(O)=O.FC1=C(OC2=C(C(C=C3OCCCN4CCCC4)=NC=N2)C=C3OC)C=CC5=C1C=C(C)N5