Cediranib maleate

Name: Cediranib maleate
SKU: A21857
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A21857

VEGFR 抑制剂

Cediranib maleate (AZD-2171 maleate) 是一种高效的、可口服的 VEGFR 抑制剂，其 IC50 值分别针对 Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit 为 <1, <3, 5, 5, 36, 2 nM。

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Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥385.00	现货
25mg	¥805.00	现货
50mg	¥1,330.00	现货
100mg	¥2,520.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

Cediranib maleate (AZD-2171 maleate) is a highly potent, orally available VEGFR inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively.

Targets

Target	Value

产品信息

目录号	A21857
分子式	C29H31FN4O7
分子量	566.58
CAS号	857036-77-2
SMILES	O=C(O)/C=C\C(O)=O.FC1=C(OC2=C(C(C=C3OCCCN4CCCC4)=NC=N2)C=C3OC)C=CC5=C1C=C(C)N5
其他名称	AZD-2171 maleate, AZD2171, AZD 2171
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	92 mg/mL (162.37 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.65 mL	88.25 mL	176.5 mL
0.5 mM	3.53 mL	17.65 mL	35.3 mL
1 mM	1.76 mL	8.82 mL	17.65 mL
5 mM	0.35 mL	1.76 mL	3.53 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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