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Celastrol

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产品目录号: A10192

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Celastrol 10mg A10192-10
¥ 500.00
Celastrol 25mg A10192-25
¥ 1,200.00
Celastrol 50mg A10192-50
¥ 2,200.00
Celastrol 100mg A10192-100
¥ 3,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Celastrol is a triterpenoid antioxidant compound isolated from the Chinese Thunder of God vine (T. wilfordii). In an isolated rat liver assay of lipid peroxidation, celastrol had an IC50 value of 7 µM, equivalent to about 15 times the antioxidant potency of α-tocopherol.

Celastrol

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Celastrol 发表的文献 (1)
  • Abdin AA, .et al. Modulatory effect of celastrol on Th1/Th2 cytokines profile, TLR2 and CD3+ T-lymphocyte expression in a relapsing-remitting model of multiple sclerosis in rats., Eur J Pharmacol., 2014, 742:102-12 PMID: 25218987

Chemical Information

目录号 A10192
Mechanism of action
分子量 450.6
化学分子式 C29H38O4
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 34157-83-0
Synonyms N/A
SMILES code CC1=C(C(=O)C=C2C1=CC=C3[C@]2(CC[C@@]4([C@@]3(CC[C@@]5([C@H]4C[C@](CC5)(C)C(=O)O)C)C)C)C)O
化学名称 3-​hydroxy-​9β,​13α-​dimethyl-​2-​oxo-​24,​25,​26-​trinoroleana-​1(10),​3,​5,​7-​tetraen-​29-​oic acid

生物活性

Description

Celastrol is a triterpenoid antioxidant compound isolated from the Chinese Thunder of God vine (T. wilfordii). In an isolated rat liver assay of lipid peroxidation, celastrol had an IC50 value of 7 µM, equivalent to about 15 times the antioxidant potency of α-tocopherol.

Targets
20S proteasome 20S proteasome
N/A2.5 μM

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.19 mL 110.96 mL 221.93mL
0.5 mM 4.44 mL 22.19 mL 44.39 mL
1 mM 2.22 mL 11.1 mL 22.19 mL
5 mM 0.44 mL 2.22 mL 4.44 mL

*The above data is based on the productmolecular weight 450.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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