CEP-18770 (Delanzomib)

目录号: A11145

Proteasome 抑制剂

CEP-18770 (Delanzomib) Chemical Structure

CAS NO. 847499-27-8

CEP-18770 (Delanzomib)是一种新型口服活性蛋白酶体抑制剂,IC50为3.8 nM,具有良好的肿瘤选择性,可用于治疗对蛋白酶体抑制有反应的MM和其他恶性肿瘤。

库存: 现货 Shipped in 7-10 Days

规格 价格 数量
5 mg
¥ 700.00
10 mg
¥ 1,200.00
50 mg
¥ 3,500.00
100 mg
¥ 6,000.00
10mM * 1mL in DMSO
¥ 1,170.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

CEP-18770 (Delanzomib)是一种新型口服活性蛋白酶体抑制剂,IC50为3.8 nM,具有良好的肿瘤选择性,可用于治疗对蛋白酶体抑制有反应的MM和其他恶性肿瘤。
靶点信息
Chymotrypsin-like proteasome
3.8 nM
In vitro DMSO 83 mg/mL (200.83 mM)
Water <1 mg/mL (<1 mM)
Ethanol 83 mg/mL (200.83 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.2 mL 120.98 mL 241.95 mL
0.5 mM 4.84 mL 24.2 mL 48.39 mL
1 mM 2.42 mL 12.1 mL 24.2 mL
5 mM 0.48 mL 2.42 mL 4.84 mL

*The above data is based on the productmolecular weight 413.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11145
MECHANISM OF ACTION Inhibitor
M. Wt 413.3
Formula C21H28BN3O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 847499-27-8
Synonyms CEP18770
SMILES B([C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)C1=CC=CC(=N1)C2=CC=CC=C2)(O)O

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