CEP-32496
目录号: A13772
Raf 抑制剂
CEP-32496 是一种口服可用的 v-raf 鼠肉瘤病毒癌基因同源物 B1（B-raf）丝氨酸/苏氨酸蛋白激酶抑制剂，具有潜在的抗肿瘤活性。
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生物活性
| Discription | CEP-32496 is an orally available v-raf murine sarcoma viral oncogene homolog B1 (B-raf) serine/threonine protein kinase inhibitor with potential antineoplastic activity. | |||||
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产品信息
| 目录号 | A13772 |
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| 分子式 | C24H22F3N5O5 |
| 分子量 | 517.5 |
| CAS号 | 1188910-76-0 |
| SMILES | CC(C)(C1=CC(=NO1)NC(=O)NC2=CC(=CC=C2)OC3=NC=NC4=CC(=C(C=C43)OC)OC)C(F)(F)F |
| 其他名称 | CEP32496, CEP 32496, AC013773, AC 013773, AC-013773 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 8 mg/mL (15.46 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 15% Captisol | 14 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.32 mL | 96.62 mL | 193.24 mL |
| 0.5 mM | 3.86 mL | 19.32 mL | 38.65 mL |
| 1 mM | 1.93 mL | 9.66 mL | 19.32 mL |
| 5 mM | 0.39 mL | 1.93 mL | 3.86 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1188910-76-0 | 1188910-76-0 供应商 | 1188910-76-0 花费 | 1188910-76-0 生产商 | 订购 1188910-76-0 | 1188910-76-0 代理商