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CEP-37440

FAK/ALK 抑制剂

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产品目录号: A15543

库存状态:中国现货中国现货

产品名 目录号 价格 数量
CEP-37440 5mg A15543-5
¥ 950.00
CEP-37440 10mg A15543-10
¥ 1,600.00
CEP-37440 25mg A15543-25
¥ 3,800.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

CEP-37440 is a novel potent and selective Dual FAK/ALK inhibitor with IC50 s of 2.3 nM (FAK) and 120 nM(ALK cellular IC50 in 75% human plasma).

CEP-37440

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Chemical Information

目录号 A15543
Mechanism of action Inhibitor
分子量 580.12
化学分子式 C30H38ClN7O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1391712-60-9
Synonyms CEP37440, CEP 37440
SMILES code CNC(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C4=C(CC(CCC4)N5CCN(CC5)CCO)C=C3)OC
化学名称 2-[[5-chloro-2-[[(6S)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-1-methoxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-2-yl]amino]pyrimidin-4-yl]amino]-N-methylbenzamide

生物活性

Description
CEP-37440 is a novel potent and selective Dual FAK/ALK inhibitor with IC50 s of 2.3 nM (FAK) and 120 nM(ALK cellular IC50 in 75% human plasma).

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.24 mL 86.19 mL 172.38mL
0.5 mM 3.45 mL 17.24 mL 34.48 mL
1 mM 1.72 mL 8.62 mL 17.24 mL
5 mM 0.34 mL 1.72 mL 3.45 mL

*The above data is based on the productmolecular weight 580.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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