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CEP33779

促销

JAK2 抑制剂

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产品目录号： A12808

库存状态：中国现货中国现货

产品名 目录号 价格 数量
CEP33779 5mg A12808-5
￥ 1,500.00
CEP33779 10mg A12808-10
￥ 2,200.00
CEP33779 25mg A12808-25
￥ 4,000.00
CEP33779 50mg A12808-50
￥ 7,200.00
CEP33779 10mM * 1mL in DMSO A12808-10mM-D
￥ 1,980.00

产品仅用于研究，不针对患者销售，望谅解.

产品简介

CEP33779 is a selective JAK2 inhibitor with IC50 of 1.8 nM.

CEP33779

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Chemical Information

目录号 A12808
Mechanism of action Inhibitor
分子量 462.57
化学分子式 C24H26N6O2S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1257704-57-6
Synonyms CEP 33779, CEP-33779
SMILES code CN1CCN(CC1)C2=CC(=CC=C2)NC3=NN4C=CC=C(C4=N3)C5=CC=C(C=C5)S(=O)(=O)C
化学名称 N-(3-(4-methylpiperazin-1-yl)phenyl)-8-(4-(methylsulfonyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine

生物活性

Description
 CEP33779 is a selective JAK2 inhibitor with IC50 of 1.8 nM.
Targets
JAK2
1.8 nM

溶解性

Solubility (25°C) * In vitro DMSO 93 mg/mL (201.05 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.62 mL 108.09 mL 216.18mL
0.5 mM 4.32 mL 21.62 mL 43.24 mL
1 mM 2.16 mL 10.81 mL 21.62 mL
5 mM 0.43 mL 2.16 mL 4.32 mL

*The above data is based on the productmolecular weight 462.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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