Certepetide
目录号: A22823
Certepetide(CEND-1),也被称为iRGD,是一种双功能环状肽。Certepetide 通过RGD基序与alphav-integrins的相互作用以及激活NRP-1,增强肿瘤的渗透性,并将固态肿瘤微环境转变为临时的传递通道。Certepetide 在肿瘤中积聚,并被用于研究胰腺癌和其他固态肿瘤。
Discription | Certepetide (CEND-1) is a bifunctional cyclic peptide (a.k.a. iRGD). Certepetide is a tumor-penetrating enhancer via RGD motif interaction with alphav-integrins and via activating NRP-1, and transforms the solid tumor microenvironment into a temporary agent conduit. Certepetide accumulates in tumors, and is used in the research of pancreatic cancer and other solid tumors. |
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目录号 | A22823 |
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分子式 | C37H60N14O14S2 |
分子量 | 989.09 |
CAS号 | 2580154-02-3 |
Sequence shortening | Ac-CRGDKGPDC-NH2 (Disulfide bridge: Cys1-Cys9) |
其他名称 | CEND-1; iRGD |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2