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Cevipabulin (TTI-237)

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产品目录号: A12591

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Cevipabulin (TTI-237) 5mg A12591-5
¥ 1,200.00
Cevipabulin (TTI-237) 10mg A12591-10
¥ 2,000.00
Cevipabulin (TTI-237) 25mg A12591-25
¥ 4,000.00
Cevipabulin (TTI-237) 50mg A12591-50
¥ 6,800.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Cevipabulin (TTI-237), an antimicrotubule agent, is a small synthetic molecule of triazolopyrimidine derivative with potential antitumor activity. With a novel mechanism of action distinct from the action of other vinca alkaloid compounds, TTI-237 specifically binds to tubulin at the vinca site, and promotes the polymerization of tubulin into microtubules.

Cevipabulin (TTI-237)

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Chemical Information

目录号 A12591
Mechanism of action N/A
分子量 464.82
化学分子式 C18H18ClF5N6O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 849550-05-6
Synonyms TTI237, D06576
SMILES code C[C@@H](C(F)(F)F)NC1=C(C(=NC2=NC=NN12)Cl)C3=C(C=C(C=C3F)OCCCNC)F
化学名称 5-Chloro-6-[2,6-difluoro-4-[3-(methylamino)propoxy]phenyl]-N-((1S)-2,2,2-trifluoro-1-methylethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

生物活性

Description
Cevipabulin (TTI-237), an antimicrotubule agent, is a small synthetic molecule of triazolopyrimidine derivative with potential antitumor activity. With a novel mechanism of action distinct from the action of other vinca alkaloid compounds, TTI-237 specifically binds to tubulin at the vinca site, and promotes the polymerization of tubulin into microtubules.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.51 mL 107.57 mL 215.14mL
0.5 mM 4.3 mL 21.51 mL 43.03 mL
1 mM 2.15 mL 10.76 mL 21.51 mL
5 mM 0.43 mL 2.15 mL 4.3 mL

*The above data is based on the productmolecular weight 464.82. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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