Cevostamab (BFCR4350A; RG6160; RO7187797) is a humanized IgG1-based bispecific antibody (BsAb) designed to target the membrane-proximal extracellular domain of FcRH5 on multiple myeloma (MM) cells, as well as CD3 on T cells. This dual targeting promotes efficient synapse formation between T cells and MM tumor cells, enhancing the cytotoxic activity of T cells against the tumor cells. Cevostamab's unique mechanism of action makes it a valuable tool for research in immuno-oncology and the therapeutic targeting of multiple myeloma.
Cevostamab (BFCR4350A; RG6160; RO7187797) is a humanized IgG1-based bispecific antibody (BsAb) designed to target the membrane-proximal extracellular domain of FcRH5 on multiple myeloma (MM) cells, as well as CD3 on T cells. This dual targeting promotes efficient synapse formation between T cells and MM tumor cells, enhancing the cytotoxic activity of T cells against the tumor cells. Cevostamab's unique mechanism of action makes it a valuable tool for research in immuno-oncology and the therapeutic targeting of multiple myeloma.
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