CFTR-Inhibitor-II

Name: CFTR-Inhibitor-II
SKU: A13723
Price: 175 CNY
Rating: 5 (1 reviews)

目录号: A13723

CFTR 抑制剂

1 篇发表文献

CFTR 抑制剂 II，亦称为 GlyH-101，是一种甘氨酸肼，能够选择性且可逆地阻断 CFTR 通道（Ki = 4.3 uM）。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥280.00	现货
5mg	¥490.00	现货
10mg	¥805.00	现货
25mg	¥1,715.00	现货
50mg	¥3,360.00	现货
100mg	¥5,040.00	现货
200mg	¥6,650.00	现货
*10mM 1mL in DMSO**	¥560.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用CFTR-Inhibitor-II发表的1篇文献

Dao-Lai Zhang, .et al. , eLife, 2018, 7: e33432 PMID: 29393851

生物活性

Discription

CFTR inhibitor II, also known as GlyH-101, is a glycine hydrazide that selectively and reversibly blocks the CFTR channel (Ki = 4.3 uM).

Targets

Target	Value

产品信息

目录号	A13723
分子式	C19H15Br2N3O3
分子量	493.2
CAS号	328541-79-3
SMILES	C1=CC=C2C=C(C=CC2=C1)NCC(=O)NN/C=C/3\C=C(C(=C(C3=O)Br)O)Br
其他名称	GlyH-101, Cystic Fibrosis Transmembrane Conductance, Regulator Inhibitor II
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	91 mg/mL (184.53 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.28 mL	101.38 mL	202.76 mL
0.5 mM	4.06 mL	20.28 mL	40.55 mL
1 mM	2.03 mL	10.14 mL	20.28 mL
5 mM	0.41 mL	2.03 mL	4.06 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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