CGI1746

目录号: A11348

BTK inhibitor

CGI1746 Chemical Structure

CAS NO. 910232-84-7

CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation.

库存: 现货

规格 价格 数量
5 mg
¥ 650.00
10 mg
¥ 1,000.00
25 mg
¥ 1,800.00
10mM * 1mL in DMSO
¥ 1,100.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation.
Targets
BTK
1.9 nM
In vitro DMSO 100 mg/mL (172.5 mM)
Water <1 mg/mL (<1 mM)
Ethanol 100 mg/mL (172.5 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.25 mL 86.25 mL 172.5 mL
0.5 mM 3.45 mL 17.25 mL 34.5 mL
1 mM 1.73 mL 8.63 mL 17.25 mL
5 mM 0.35 mL 1.73 mL 3.45 mL

*The above data is based on the productmolecular weight 579.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11348
MECHANISM OF ACTION Inhibitor
M. Wt 579.7
Formula C34H37N5O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 910232-84-7
Synonyms CGI 1746, CGI-1746
SMILES CC1=C(C=CC=C1NC(=O)C2=CC=C(C=C2)C(C)(C)C)C3=CN(C(=O)C(=N3)NC4=CC=C(C=C4)C(=O)N5CCOCC5)C

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