CGI1746
目录号: A11348
BTK 抑制剂
CGI1746 是一种小分子 Btk 抑制剂 化学类型，具有新的结合模式，能够稳定非磷酸化酶的非活性构象。
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生物活性
| Discription | CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. | ||
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产品信息
| 目录号 | A11348 |
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| 分子式 | C34H37N5O4 |
| 分子量 | 579.7 |
| CAS号 | 910232-84-7 |
| SMILES | CC1=C(C=CC=C1NC(=O)C2=CC=C(C=C2)C(C)(C)C)C3=CN(C(=O)C(=N3)NC4=CC=C(C=C4)C(=O)N5CCOCC5)C |
| 其他名称 | CGI 1746, CGI-1746 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 91 mg/mL (156.98 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 30 mg/mL (51.75 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.25 mL | 86.25 mL | 172.5 mL |
| 0.5 mM | 3.45 mL | 17.25 mL | 34.5 mL |
| 1 mM | 1.73 mL | 8.63 mL | 17.25 mL |
| 5 mM | 0.35 mL | 1.73 mL | 3.45 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 910232-84-7 | 910232-84-7 供应商 | 910232-84-7 花费 | 910232-84-7 生产商 | 订购 910232-84-7 | 910232-84-7 代理商