CGK 733
目录号: A13191
ATM/ATR 抑制剂
CGK733 是一种选择性的 ATR 和 ATM 激酶抑制剂。能够诱导过早衰老的乳腺癌细胞死亡。
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生物活性
| Discription | CGK733 is a selective inhibitor of ATR and ATM kinases. Induces cell death in prematurely senescent breast cancer cells. | ||
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产品信息
| 目录号 | A13191 |
|---|---|
| 分子式 | C23H18Cl3FN4O3S |
| 分子量 | 555.84 |
| CAS号 | 905973-89-9 |
| SMILES | C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)NC(C(Cl)(Cl)Cl)NC(=S)NC3=CC(=C(C=C3)F)[N+](=O)[O-] |
| 其他名称 | CGK733,CGK-733 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 90 mg/mL (161.91 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.99 mL | 89.95 mL | 179.91 mL |
| 0.5 mM | 3.6 mL | 17.99 mL | 35.98 mL |
| 1 mM | 1.8 mL | 9 mL | 17.99 mL |
| 5 mM | 0.36 mL | 1.8 mL | 3.6 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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