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CGP77675是有效的Src激酶抑制剂。CGP77675抑制了肽底物的磷酸化和纯化Src的自磷酸化（分别为IC50：5-20和40 nM）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.55 mL | 112.73 mL | 225.46 mL |
| 0.5 mM | 4.51 mL | 22.55 mL | 45.09 mL |
| 1 mM | 2.25 mL | 11.27 mL | 22.55 mL |
| 5 mM | 0.45 mL | 2.25 mL | 4.51 mL |
*The above data is based on the productmolecular weight 443.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13821 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 443.54 |
| Formula | C26H29N5O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 234772-64-6 |
| Synonyms | CGP 77675, CGP-77675 |
| SMILES | COC1=CC=CC(=C1)C2=CN(C3=C2C(=NC=N3)N)C4=CC=C(C=C4)CCN5CCC(CC5)O |
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