Chaetocin

目录号: A12812

SUV39H HMT Inhibitor

Chaetocin Chemical Structure

CAS NO. 28097-03-2

Chaetocin is a histone methyltransferase SUV39H1 inhibitor (IC50 = 0.8 μM). Induces apoptosis in myeloma cell lines in vitro; exhibits antiproliferative activity in a mouse myeloma model in vivo.

库存: 缺货

规格 价格
1 mg
¥ 850.00
2 mg
¥ 1,500.00
5 mg
¥ 3,000.00
10 mg
¥ 5,000.00
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详情

Chaetocin is a histone methyltransferase SUV39H1 inhibitor (IC50 = 0.8 μM). Induces apoptosis in myeloma cell lines in vitro; exhibits antiproliferative activity in a mouse myeloma model in vivo.
Targets
dSU(VAR)3-9 mouse G9a Neurospora crassa DIM5
0.8 μM2.5 μM3 μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.35 mL 71.75 mL 143.5 mL
0.5 mM 2.87 mL 14.35 mL 28.7 mL
1 mM 1.44 mL 7.18 mL 14.35 mL
5 mM 0.29 mL 1.44 mL 2.87 mL

*The above data is based on the productmolecular weight 696.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A12812
MECHANISM OF ACTION Inhibitor
M. Wt 696.84
Formula C30H28N6O6S4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 28097-03-2
Synonyms N/A
SMILES CN1C(=O)C23CC4(C(N2C(=O)C1(SS3)CO)NC5=CC=CC=C54)C67CC89C(=O)N(C(C(=O)N8C6NC1=CC=CC=C71)(SS9)CO)C

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