CHF5074
目录号: A16214
γ-Secretase modulator
CHF5074 是一种新型的 γ-secretase 调节剂，能够降低 Aβ42 和 Aβ40 的分泌，其 IC50 分别为 3.6 和 18.4 uM。
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生物活性
| Discription | CHF5074 is a novel γ-secretase modulator, reduces Aβ42 and Aβ40 secretion, with an IC50 of 3.6 and 18.4 uM, respectively. |
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产品信息
| 目录号 | A16214 |
|---|---|
| 分子式 | C16H11Cl2FO2 |
| 分子量 | 325.16 |
| CAS号 | 749269-83-8 |
| SMILES | O=C(C1(C2=CC=C(C3=CC=C(Cl)C(Cl)=C3)C(F)=C2)CC1)O |
| 其他名称 | CSP-1103, CHF-5074 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 51 mg/mL (156.84 mM) | |
| Water | Insoluble | ||
| Ethanol | 8 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.75 mL | 153.77 mL | 307.54 mL |
| 0.5 mM | 6.15 mL | 30.75 mL | 61.51 mL |
| 1 mM | 3.08 mL | 15.38 mL | 30.75 mL |
| 5 mM | 0.62 mL | 3.08 mL | 6.15 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 749269-83-8 | 749269-83-8 供应商 | 749269-83-8 花费 | 749269-83-8 生产商 | 订购 749269-83-8 | 749269-83-8 代理商