CHIR-124

目录号: A11046

CHK Inhibitor

CHIR-124

CHIR-124 Chemical Structure

CAS NO. 405168-58-3

CHIR-124 is a novel and potent Chk1 inhibitor (IC50: 0.32 nM and 697 nM for Chk1 and Chk2 respectively).

库存: 现货

规格 价格 数量
5 mg
¥ 700.00
10 mg
¥ 1,200.00
25 mg
¥ 2,200.00
100 mg
¥ 6,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

CHIR-124 is a novel and potent Chk1 inhibitor (IC50: 0.32 nM and 697 nM for Chk1 and Chk2 respectively).
Targets
Target Value
Chk1IC50: 0.3nM
FLT3IC50: 5.8nM
PDGFRIC50: 6.6nM
GSK-3IC50: 23.3nM
FynIC50: 98.8nM
PKAIC50: 103.1nM
PKCγIC50: 110nM
LCKIC50: 158.3nM
CDK2/CyclinAIC50: 191.1nM
VEGFR1/FLT1IC50: 463.6nM
Cdc2/CyclinBIC50: 505.7nM
VEGFR2/Flk1IC50: 577.9nM
PKCβ2IC50: 580nM
PKCαIC50: 580nM
Chk2IC50: 697.4nM
FGFR3IC50: 1.29μM
bFGFRIC50: 2.04μM
CDK4/CyclinDIC50: 2.05μM
PKAβ1IC50: 2.25μM
c-MetIC50: >3μM
ERK2IC50: 4.31μM
CABLIC50: 14.88μM
In vitro (25°C) DMSO 7 mg/mL (16.67 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.82 mL 119.08 mL 238.15 mL
0.5 mM 4.76 mL 23.82 mL 47.63 mL
1 mM 2.38 mL 11.91 mL 23.82 mL
5 mM 0.48 mL 2.38 mL 4.76 mL

*The above data is based on the productmolecular weight 419.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A11046
MECHANISM OF ACTION Inhibitor
M. Wt 419.9
Formula C23H22ClN5O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 405168-58-3
Synonyms CHIR124
SMILES C1CN2CCC1[C@@H](C2)NC3=C4C=C(C=CC4=NC(=O)C3=C5NC6=CC=CC=C6N5)Cl

产品标签

产品标签

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
您还可能对下列产品感兴趣
Keywords:购买 CHIR-124 | CHIR-124 供应商 | 订购 CHIR-124 | CHIR-124 价格 | CHIR-124 生产商 | 订单 CHIR-124 | CHIR-124 代理商 | 购买 405168-58-3| 405168-58-3 供应商 | 订购 405168-58-3 | 405168-58-3 价格 | 405168-58-3 生产商 | 订单 405168-58-3 | 405168-58-3 代理商|buy CHIR-124 | CHIR-124 Supplier | purchase CHIR-124 | CHIR-124 cost | CHIR-124 manufacturer | order CHIR-124 | CHIR-124 distributor | buy 405168-58-3| 405168-58-3 Supplier | purchase 405168-58-3 | 405168-58-3 cost | 405168-58-3 manufacturer | order 405168-58-3 | 405168-58-3 distributor
Rewards