CHMFL-ABL-039
目录号: A13182
BCR-ABL 抑制剂
CHMFL-ABL-039 是一种 II型原生ABL激酶 和 耐药性V299L突变BCR-ABL抑制剂,其半抑制浓度(IC50)分别为7.9 nM和27.9 nM。CHMFL-ABL-039 用于慢性髓性白血病的研究。
Discription | CHMFL-ABL-039 is a type II native ABL kinase and drug-resistant V299L mutant BCR-ABL inhibitor with the IC50s of 7.9 nM and 27.9 nM, respectively. CHMFL-ABL-039 is used in the research of chronic myeloid leukemia. |
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目录号 | A13182 |
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分子式 | C31H33F3N6O3 |
分子量 | 594.63 |
CAS号 | 2304344-56-5 |
SMILES | O=C(NC1=CN=C(NC(C2CC2)=O)C=C1)CC3=CC=C(NC(C4=CC=C(CN5CCN(C)CC5)C(C(F)(F)F)=C4)=O)C=C3 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2