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CHMFL-ABL-039

目录号: A13182
BCR-ABL 抑制剂
CHMFL-ABL-039 是一种 II型原生ABL激酶耐药性V299L突变BCR-ABL抑制剂,其半抑制浓度(IC50)分别为7.9 nM和27.9 nM。CHMFL-ABL-039 用于慢性髓性白血病的研究。
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1mg
¥2,240.00
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5mg
¥6,720.00
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10mg
¥11,200.00
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生物活性
Discription CHMFL-ABL-039 is a type II native ABL kinase and drug-resistant V299L mutant BCR-ABL inhibitor with the IC50s of 7.9 nM and 27.9 nM, respectively. CHMFL-ABL-039 is used in the research of chronic myeloid leukemia.
产品信息
目录号 A13182
分子式 C31H33F3N6O3
分子量 594.63
CAS号 2304344-56-5
SMILES O=C(NC1=CN=C(NC(C2CC2)=O)C=C1)CC3=CC=C(NC(C4=CC=C(CN5CCN(C)CC5)C(C(F)(F)F)=C4)=O)C=C3
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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